Recent advances in metal–organic frameworks for stimuli-responsive drug delivery

Author:

Xing Fei1ORCID,Xu Jiawei1,Zhou Yuxi2,Yu Peiyun3,Zhe Man4,Xiang Zhou1,Duan Xin15ORCID,Ritz Ulrike6ORCID

Affiliation:

1. Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China

2. Department of Periodontology, Justus-Liebig-University of Giessen, Germany

3. LIMES Institute, Department of Molecular Brain Physiology and Behavior, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany

4. Animal Experiment Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China

5. Department of Orthopedic Surgery, The Fifth People's Hospital of Sichuan Province, Chengdu, China

6. Department of Orthopaedics and Traumatology, Biomatics Group, University Medical Center of the Johannes Gutenberg University, Langenbeckstr. 1, 55131 Mainz, Germany

Abstract

Metal-organic frameworks have become promising stimuli-responsive agents to release the loaded therapeutic agents in the target site to achieve more precise drug delivery due to their high drug loading, excellent biocompatibility, and high stimuli-responsiveness.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Sichuan Province

Chinesisch-Deutsche Zentrum für Wissenschaftsförderung

Publisher

Royal Society of Chemistry (RSC)

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