Coupling of acceptor-substituted diazo compounds and tertiary thioamides: synthesis of enamino carbonyl compounds and their pharmacological evaluation-Reference-Cited by-同舟云学术

Coupling of acceptor-substituted diazo compounds and tertiary thioamides: synthesis of enamino carbonyl compounds and their pharmacological evaluation

Published:2022 Issue:30 Volume:12 Page:19431-19444
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Secka Jim¹,Pal Arpan¹,Acquah Francis A.²³⁴^ORCID,Mooers Blaine H. M.²³⁴^ORCID,Karki Anand B.⁵,Mahjoub Dania⁵,Fakhr Mohamed K.⁵,Wallace David R.⁶,Okada Takuya⁷,Toyooka Naoki⁷,Kuta Adama¹,Koduri Naga¹,Herndon Deacon¹,Roberts Kenneth P.¹,Wang Zhiguo¹,Hileman Bethany¹,Rajagopal Nisha¹,Hussaini Syed R.¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, The University of Tulsa, 800 S. Tucker Drive, Tulsa, Oklahoma 74104, USA

2. Department of Biochemistry and Molecular Biology, University of Oklahoma of Health Sciences Center, Oklahoma City, OK 73104, Unites States

3. Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA

4. Laboratory of Biomolecular Structure and Function, University of Oklahoma of Health Sciences Center, Oklahoma City, OK 73104, USA

5. Department of Biological Science, The University of Tulsa, 800 S. Tucker Drive, Tulsa, Oklahoma 74104, USA

6. Department of Pharmacology and Physiology, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma 74107, USA

7. Faculty of Engineering, University of Toyama, 3190 Gofuku, Toyama, 930-8555, Japan

Abstract

This paper describes the synthesis of enamino carbonyl compounds by the copper(i)-catalyzed coupling of acceptor-substituted diazo compounds and tertiary thioamides.

Funder

National Science Foundation

Oklahoma Center for the Advancement of Science and Technology

National Institutes of Health

Oklahoma State University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA02415B

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4. Diversity-Oriented Approach to N-Heterocyclic Compounds from α-Phenyl-β-enamino Ester via a Mitsunobu-Michael Reaction Sequence

5. A Study of the Reactions of 3‐Bromopropenals with Anilines for the Synthesis of α‐Bromo Enaminones

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