Platin-<i>C</i> containing nanoparticles: a recipe for the delivery of curcumin–cisplatin combination chemotherapeutics to mitochondria-Reference-Cited by-同舟云学术

Platin-C containing nanoparticles: a recipe for the delivery of curcumin–cisplatin combination chemotherapeutics to mitochondria

Published:2023 Issue:12 Volume:52 Page:3575-3585
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Banik Bhabatosh¹²³⁴^ORCID,Ashokan Akash¹²^ORCID,Choi Joshua H.³,Surnar Bapurao¹²,Dhar Shanta¹²³⁵^ORCID

Affiliation:

1. NanoTherapeutics Research Laboratory, Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA

2. Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 33136, USA

3. Nano Therapeutics Research Laboratory, Department of Chemistry, University of Georgia, Athens, GA 30602, USA

4. Department of Chemistry, Cotton University, Panbazar, Guwahati-781001, Assam, India

5. Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA

Abstract

We report the synthesis of a curcumin–cisplatin combination chemotherapeutic agent, Platin-C, suitably packaged in a mitochondrion-targeted nanovehicle for enhanced anticancer efficacy and diminished chemotherapy-associated inflammation.

Funder

U.S. Department of Defense

Sylvester Comprehensive Cancer Center, University of Miami Health Systems

Florida Department of Health

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D2DT03149C

Reference59 articles.