Cardiomyocyte dedifferentiation and remodeling in 3D scaffolds to generate the cellular diversity of engineering cardiac tissues

Author:

Wang Changyong12345ORCID,Liu Wei12345,Shen Yuan12345,Chen Jiayun6789,Zhu Huimin12345,Yang Xiaoning12345,Jiang Xiaoxia12345,Wang Yan12345,Zhou Jin12345ORCID

Affiliation:

1. Tissue Engineering Research Center

2. Academy of Military Medical Sciences and Department of Neural Engineering and Biological Interdisciplinary Studies

3. Institute of Military Cognition and Brain Sciences

4. Academy of Military Medical Sciences

5. Beijing 100850

6. College of Life Science and Technology

7. Huazhong Agricultural university

8. Wuhan 430070

9. PR China

Abstract

The use of engineered cardiac tissues (ECTs) is a new strategy for the repair and replacement of cardiac tissues in patients with myocardial infarction, particularly at late stages.

Funder

National Basic Research Program of China

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China

National Natural Science Foundation of China

Beijing Nova Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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