Selective formation of phthalimides from amines, aldehydes and CO by Pd-catalyzed oxidative C–H aminocarbonylation-Reference-Cited by-同舟云学术

Selective formation of phthalimides from amines, aldehydes and CO by Pd-catalyzed oxidative C–H aminocarbonylation

Published:2018 Issue:12 Volume:5 Page:1957-1961
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Shi Renyi¹²³⁴⁵,Liao Fan⁶⁷⁸⁵,Niu Huiying¹²³⁴⁵,Lei Aiwen¹²³⁴⁵^ORCID

Affiliation:

1. College of Chemistry and Molecular Sciences

2. Institute for Advanced Studies (IAS)

3. Wuhan University

4. Wuhan 430072

5. P. R. China

6. National Research Center for Carbohydrate Synthesis

7. Jiangxi Normal University

8. Nanchang 330022

Abstract

The Pd/Cu-catalyzed intramolecular C–H bond aminocarbonylation utilizing imines as the amine source has been developed. This transformation provides an efficient and straightforward protocol for the synthesis of phthalimides which widely exist in natural products, pharmaceutical and functional materials. Various functional groups are tolerated and the yields are up to 99%.

Funder

National Natural Science Foundation of China

Ministry of Science and Technology of the People's Republic of China

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/QO/C8QO00282G

Reference88 articles.

1. Palladium-Catalyzed Carbonylation Reactions of Aryl Halides and Related Compounds