Synthesis and photobiological applications of naphthalimide–benzothiazole conjugates: cytotoxicity and topoisomerase IIα inhibition-Reference-Cited by-同舟云学术

Synthesis and photobiological applications of naphthalimide–benzothiazole conjugates: cytotoxicity and topoisomerase IIα inhibition

Published:2022 Issue:1 Volume:12 Page:483-497
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Singh Iqubal¹,Luxami Vijay¹^ORCID,Choudhury Diptiman¹^ORCID,Paul Kamaldeep¹^ORCID

Affiliation:

1. School of Chemistry and Biochemistry, Thapar Institute of Engineering and Technology, Patiala-147001, India

Abstract

Conjugates of naphthalimide, benzothiazole, and indole moieties are synthesized that show excellent cytotoxicity against A549 (lung), MCF7 (breast), and HeLa (cervix) cancer cell lines with IC50 values in the range of 0.14–8.59 μM.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D1RA04148G

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