Acid-triggered release of doxorubicin from a hydrazone-linked Gd3+-texaphyrin conjugate-Reference-Cited by-同舟云学术

Acid-triggered release of doxorubicin from a hydrazone-linked Gd3+-texaphyrin conjugate

Published:2016 Issue:69 Volume:52 Page:10551-10554
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Lee Min Hee¹²³⁴,Kim Eun-Joong⁵⁶⁷⁴,Lee Hyunseung⁵⁶⁷⁴,Park Sun Young¹²³⁴,Hong Kwan Soo⁵⁶⁷⁴,Kim Jong Seung¹⁸⁹⁴,Sessler Jonathan L.¹¹⁰¹¹¹²

Affiliation:

1. Department of Chemistry

2. Sookmyung Women's University

3. Seoul 04310

4. Korea

5. Bioimaging Research Team

6. Korea Basic Science Institute

7. Cheongju 28119

8. Korea University

9. Seoul 02841

10. University of Texas at Austin

11. Austin

12. USA

Abstract

The hydrazone-based Gd³⁺-texaphyrin doxorubicin conjugate 1, releases active doxorubicin at acidic pH values, allowing its components to be followed by two complementary imaging methods, namely Off–On fluorescence enhancement and MR imaging.

Funder

Korea Basic Science Institute

National Research Foundation

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC05673C

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