The protecting-group free selective 3′-functionalization of nucleosides-Reference-Cited by-同舟云学术

The protecting-group free selective 3′-functionalization of nucleosides

Published:2017 Issue:4 Volume:8 Page:2804-2810
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

McCabe Dunn Jamie M.¹²³⁴⁵^ORCID,Reibarkh Mikhail¹²³⁴⁵,Sherer Edward C.⁶²³⁴⁵^ORCID,Orr Robert K.¹²³⁴⁵^ORCID,Ruck Rebecca T.¹²³⁴⁵^ORCID,Simmons Bryon¹²³⁴⁵,Bellomo Ana¹²³⁴⁵

Affiliation:

1. Department of Process Research & Development

2. MRL

3. Merck & Co., Inc.

4. Rahway

5. USA

6. Department of Modelling and Informatics

Abstract

The direct and chemoselective 3′-phosphoramidation, phosphorylation and acylation of nucleosides are described.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C6SC05081F

Reference55 articles.

1. Chemoselectivity and the Curious Reactivity Preferences of Functional Groups

2. Protecting-group-free synthesis as an opportunity for invention

3. Protecting-Group-Free Synthesis

4. METABOLISM OF GS-7340, A NOVEL PHENYL MONOPHOSPHORAMIDATE INTRACELLULAR PRODRUG OF PMPA, IN BLOOD

5. Medicinal Chemistry of Nucleoside Phosphonate Prodrugs for Antiviral Therapy

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