Influence of the nanofiber chemistry and orientation of biodegradable poly(butylene succinate)-based scaffolds on osteoblast differentiation for bone tissue regeneration

Author:

Cristofaro Francesco12345ORCID,Gigli Matteo6789ORCID,Bloise Nora12345ORCID,Chen Honglin10111213,Bruni Giovanna1415459ORCID,Munari Andrea1617181920ORCID,Moroni Lorenzo1011121321ORCID,Lotti Nadia1617181920ORCID,Visai Livia12345ORCID

Affiliation:

1. Molecular Medicine Department (DMM)

2. Center for Health Technologies (CHT)

3. UdR INSTM

4. University of Pavia

5. 27100 Pavia

6. Department of Chemical Science and Technologies

7. University of Roma Tor Vergata

8. 00133 Roma

9. Italy

10. MERLN Institute for Technology Inspired Regenerative Medicine

11. Department of Complex Tissue Regeneration

12. Maastricht University

13. The Netherlands

14. Department of Chemistry

15. Section of Physical Chemistry

16. Department of Civil

17. Chemical

18. Environmental and Materials Engineering

19. University of Bologna

20. 40131 Bologna

21. CNR NANOTEC Institute of Nanotechnology

Abstract

Ether-linkages present in copolymer macromolecular chains and nanofiber topography exert a synergistic effect in improving osteoblast adhesion and differentiation.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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