Evaluation of DFO-HOPO as an octadentate chelator for zirconium-89-Reference-Cited by-同舟云学术

Evaluation of DFO-HOPO as an octadentate chelator for zirconium-89

Published:2017 Issue:61 Volume:53 Page:8529-8532
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Allott L.¹²³⁴^ORCID,Da Pieve C.¹²³⁴,Meyers J.⁵⁶²³⁴^ORCID,Spinks T.¹²³⁴,Ciobota D. M.¹²³⁴,Kramer-Marek G.¹²³⁴^ORCID,Smith G.¹²³⁴^ORCID

Affiliation:

1. Division of Radiotherapy and Imaging

2. The Institute of Cancer Research

3. London

4. UK

5. Cancer Research UK Cancer Therapeutics Unit

6. Division of Cancer Therapeutics

Abstract

The future of ⁸⁹Zr-based immuno-PET is reliant upon the development of new chelators with improved stability compared to the currently used deferoxamine (DFO).

Funder

National Institute for Health Research

Cancer Research UK

Wellcome Trust

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/CC/C7CC03572A

Reference21 articles.

1. PET imaging with 89Zr: From radiochemistry to the clinic

2. 89Zr, a Radiometal Nuclide with High Potential for Molecular Imaging with PET: Chemistry, Applications and Remaining Challenges

3. Immuno-Positron Emission Tomography with Zirconium-89-Labeled Monoclonal Antibodies in Oncology: What Can We Learn from Initial Clinical Trials?

4. ⁸⁹Zr-PET Radiochemistry in the Development and Application of Therapeutic Monoclonal Antibodies and Other Biologicals

5. 89Zr Radiochemistry for Positron Emission Tomography

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