Design and synthesis of a clickable, photoreactive amino acid <i>p</i>-(4-(but-3-yn-1-yl)benzoyl)-<scp>l</scp>-phenylalanine for peptide photoaffinity labeling-Reference-Cited by-同舟云学术

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Design and synthesis of a clickable, photoreactive amino acid p-(4-(but-3-yn-1-yl)benzoyl)-l-phenylalanine for peptide photoaffinity labeling

Published:2023 Issue:2 Volume:13 Page:866-872
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Han Penggang¹^ORCID,Wang Fuli¹,Bao Shaoheng¹,Yao Ge¹,Wan Xiukun¹,Liu JiaJia¹,Jiang Hui¹

Affiliation:

1. State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China

Abstract

The clickable and photoreactive amino acid is prepared in 11 steps from 3-(4-bromophenyl)-1-propanol.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D2RA07248C

Reference23 articles.

1. Tailor-made amino acid-derived pharmaceuticals approved by the FDA in 2019

2. Tailor-made amino acids in the design of small-molecule blockbuster drugs

3. Peptidomimetics and Peptide-Based Blockbuster Drugs

4. The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine

5. Probing G Protein-Coupled Receptor—Ligand Interactions with Targeted Photoactivatable Cross-Linkers

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