One-pot C–C, C–N, and C–S bond construction for synthesis of 3-sulfenylindoles directly from unactivated anilines involving dual palladium catalysis and mechanistic insights from DFT-Reference-Cited by-同舟云学术

One-pot C–C, C–N, and C–S bond construction for synthesis of 3-sulfenylindoles directly from unactivated anilines involving dual palladium catalysis and mechanistic insights from DFT

Published:2023 Issue:4 Volume:21 Page:838-845
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Rastogi Sumit K.¹²^ORCID,Singh Richa¹³,Kumar Santosh¹²^ORCID,Mishra Abhishek Kumar¹,Ahirwar Mini Bharati⁴^ORCID,Deshmukh Milind M.⁴^ORCID,Sinha Arun K.¹²⁵^ORCID,Kumar Ravindra¹²^ORCID

Affiliation:

1. Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow-226031, UP, India

2. Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, UP-201002, India

3. Department of Chemistry, Gaya College, Gaya, Bihar-823001, India

4. Department of Chemistry, Dr Harisingh Gour Vishwavidyalaya (A Central University), Sagar, India

5. Ranchi University, Ranchi, Jharkhand-834001, India

Abstract

An efficient dual Pd-catalytic system was developed for one-pot synthesis of 3-sulfenylindoles via C–C, C–N and C–S bond construction directly from unactivated 2-iodo(NH)anilines under mild reaction conditions.

Funder

Council of Scientific and Industrial Research, India

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D2OB01606K

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