The role of energy cost on accuracy, sensitivity, specificity, speed and adaptation of T cell foreign and self recognition
Author:
Affiliation:
1. Department of Chemistry
2. SUNY Stony Brook
3. Stony Brook
4. USA
5. Department of Physics and Astronomy
Abstract
Various physical outcomes are obtained based on a kinetic model illustrating recognitions of T cell.
Funder
National Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2021/CP/D0CP02422H
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1. U. Alon , An Introduction to Systems Biology (Design Principles of Biological Circuits) , Chapman and Hall/CRC , London , 2007
2. Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity
3. Kinetic amplification of enzyme discrimination
4. An amplified sensitivity arising from covalent modification in biological systems.
5. Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Modulation of antigen discrimination by duration of immune contacts in a kinetic proofreading model of T cell activation with extreme statistics;PLOS Computational Biology;2023-08-30
2. Modulation of antigen discrimination by duration of immune contacts in a kinetic proofreading model of T cell activation with extreme statistics;2023-06-01
3. Physical bioenergetics: Energy fluxes, budgets, and constraints in cells;Proceedings of the National Academy of Sciences;2021-06-17
4. Correction: The role of energy cost on accuracy, sensitivity, specificity, speed and adaptation of T cell foreign and self recognition;Physical Chemistry Chemical Physics;2021
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