Nitric oxide/paclitaxel micelles enhance anti-liver cancer effects and paclitaxel sensitivity by inducing ferroptosis, endoplasmic reticulum stress and pyroptosis-Reference-Cited by-同舟云学术

Nitric oxide/paclitaxel micelles enhance anti-liver cancer effects and paclitaxel sensitivity by inducing ferroptosis, endoplasmic reticulum stress and pyroptosis

Published:2023 Issue:45 Volume:13 Page:31772-31784
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Li Huilan¹,Deng Xiaoyu²,Zhang Ziwei²,Yang Zunhua²^ORCID,Huang Hesong¹,Ye Xide²,Zhong Linyun²,Xu Guoliang²,Liu Ronghua²,Fang Yuanying¹^ORCID

Affiliation:

1. National Engineering Research Center for Manufacturing Technology of TCM Solid Preparation, Jiangxi University of Chinese Medicine, Nanchang 330006, China

2. College of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China

Abstract

The paclitaxel-containing micelle bearing NO donor (NO/PTX) exhibited improved anticancer effect in Bel-7402 cells and H22 xenograft mice by the modes of ferroptosis, pyroptosis, ERS and apoptosis-associated networks.

Funder

Jiangxi Provincial Department of Science and Technology

National Natural Science Foundation of China

Education Department of Jiangxi Province

Jiangxi University of Traditional Chinese Medicine

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA04861F

Reference47 articles.