Design, synthesis, and biological evaluation of a <sup>99m</sup>Tc-labeled small-molecule tracer for PD-L1 imaging-Reference-Cited by-同舟云学术

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Design, synthesis, and biological evaluation of a ^99mTc-labeled small-molecule tracer for PD-L1 imaging

Published:2024 Issue:16 Volume:48 Page:7300-7307
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Lu Chunxiong¹^ORCID,Zhu Dandan¹²,Zhou Peng¹²,Yu Kangxia¹²,Liu Yaling¹^ORCID,Wang Hongyong¹,Wu Hao¹^ORCID,Wu Jun¹,Han Guoqing¹,Zou Pei¹^ORCID

Affiliation:

1. NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, China

2. School of Pharmacy, Nanjing Medical University, Nanjing 211166, China

Abstract

Illustration of [99mTc]Tc-SG2C-CBM for imaging PD-L1.

Funder

Jiangsu Commission of Health

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D3NJ05843C

Reference37 articles.

1. Cancer immunotherapy comes of age

2. Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: a comprehensive review of registration trials and future considerations

3. Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer

4. Combination immunotherapy for hepatocellular carcinoma

5. Ramucirumab plus pembrolizumab in patients with previously treated advanced non-small-cell lung cancer, gastro-oesophageal cancer, or urothelial carcinomas (JVDF): a multicohort, non-randomised, open-label, phase 1a/b trial

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