Dearomative [4 + 2] annulations between 3-nitroindoles and enals through oxidative N-heterocyclic carbene catalysis-Reference-Cited by-同舟云学术

Dearomative [4 + 2] annulations between 3-nitroindoles and enals through oxidative N-heterocyclic carbene catalysis

Published:2020 Issue:23 Volume:7 Page:3862-3867
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Huang Hua¹²³⁴⁵,Li Qing-Zhu⁶⁷⁸⁹¹⁰^ORCID,Liu Yan-Qing¹²³⁴⁵,Leng Hai-Jun¹²³⁴⁵,Xiang Peng⁶⁷⁸⁹¹⁰,Dai Qing-Song⁶⁷⁸⁹¹⁰,He Xiang-Hong¹²³⁴⁵^ORCID,Huang Wei¹²³⁴⁵^ORCID,Li Jun-Long⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. State Key Laboratory of Southwestern Chinese Medicine Resources

2. School of Pharmacy

3. Chengdu University of Traditional Chinese Medicine

4. Chengdu 611137

5. China

6. Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province

7. Sichuan Industrial Institute of Antibiotics

8. Chengdu University

9. Chengdu 610052

10. PR China

Abstract

A novel intermolecular dearomative [4 + 2] annulation of 3-nitroindoles and enals under oxidative N-heterocyclic carbene catalysis has been developed. This protocol was also suitable for the oxidative cyclisation of 2-nitrobenzothiophenes with enals.

Funder

National Natural Science Foundation of China

Chengdu University of Traditional Chinese Medicine

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00868K

Reference59 articles.

1. Indole synthesis – something old, something new

2. Recent advances in indole syntheses: New routes for a classic target