Investigation of supramolecular interaction of quercetin with N,N-dimethylamine-functionalized p-sulfonated calix[4,8]arenes using molecular modeling and their in vitro cytotoxic response towards selected cancer cells

Author:

Oguz Mehmet12,Dogan Berna34,Durdagi Serdar4,Bhatti Asif Ali5ORCID,Karakurt Serdar6,Yilmaz Mustafa1ORCID

Affiliation:

1. Selcuk University, Department of Chemistry, 42075 Konya, Turkey

2. Department of Advanced Material and Nanotechnology, Selcuk University, 42031 Konya, Turkey

3. Department of Biochemistry, School of Medicine, Bahcesehir University, Istanbul, Turkey

4. Computational Biology and Molecular Simulations Laboratory, Department of Biophysics, School of Medicine, Bahcesehir University, Istanbul, Turkey

5. Department of Chemistry, Government College University Hyderabad, Hyderabad, 71000, Pakistan

6. Selcuk University, Department of Biochemistry, Konya 42075, Turkey

Abstract

Although quercetin is an effective bioactive compound preventing the progress of several human cancers, its impact is reduced due to low bioavailability.

Funder

Türkiye Bilimsel ve Teknolojik Araştirma Kurumu

Selçuk Üniversitesi

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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