Programmably engineered stochastic RNA nanowalker for ultrasensitive miRNA detection

Author:

Zhu Dan12ORCID,Zhao Dongxia1,Hu Yang1,Wei Tianhui1,Su Tong1,Su Shao1ORCID,Chao Jie1ORCID,Wang Lianhui1ORCID

Affiliation:

1. State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, 9 Wenyuan Road, Nanjing 210023, China

2. State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China

Abstract

A programmably engineered stochastic RNA nanowalker powered by duplex-specific nuclease (DSN) is developed.

Funder

National Natural Science Foundation of China

Qinglan Project of Jiangsu Province of China

Natural Science Foundation of Jiangsu Province

Nanjing University of Posts and Telecommunications

Publisher

Royal Society of Chemistry (RSC)

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