A microfluidic device and instrument prototypes for the detection of Escherichia coli in water samples using a phage-based bioluminescence assay

Author:

Alonzo Luis F.1ORCID,Hinkley Troy C.1ORCID,Miller Andrew1,Calderon Ryan1,Garing Spencer1,Williford John1,Clute-Reinig Nick1,Spencer Ethan1,Friend Michael1,Madan Damian1ORCID,Dinh Van T. T.1,Bell David2ORCID,Weigl Bernhard H.1,Nugen Sam R.3ORCID,Nichols Kevin P.1,Le Ny Anne-Laure M.1ORCID

Affiliation:

1. Intellectual Ventures Laboratory, 14360 SE Eastgate Way, Bellevue, WA 98007, USA

2. Independent Consultant, Issaquah, WA 98027, USA

3. Department of Food Science, Cornell University, Ithaca, NY 14850, USA

Abstract

A phage-based microfluidic platform for highly sensitive and rapid detection of E. coli in low-resource settings.

Funder

Bill and Melinda Gates Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Reference45 articles.

1. The human right to water and sanitation , GA Res 64/292, UN GAOR, 64th sess, 108th plen mtg, Agenda Item 48, UN Doc A/RES/64/292 (adopted 28 July 2010 )

2. Transforming our world: the 2030 Agenda for Sustainable Development , GA Res 70/1, UN GAOR, 70th sess, 4th plen mtg, Agenda Item 15 and 116, UN Doc A/RES/70/1 (adopted 25 September 2015 )

3. UNICEF and WHO , Progress on household drinking water, sanitation and hygiene 2000–2017: Special focus on inequalities , 2019

4. Burden of disease from inadequate water, sanitation and hygiene in low‐ and middle‐income settings: a retrospective analysis of data from 145 countries

5. WHO , Preventing diarrhoea through better water, sanitation and hygiene: exposures and impacts in low- and middle-income countries , Geneva , 2014

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