Osmolytes modify protein dynamics and function of tetrameric lactate dehydrogenase upon pressurization-Reference-Cited by-同舟云学术

Osmolytes modify protein dynamics and function of tetrameric lactate dehydrogenase upon pressurization

Published:2019 Issue:24 Volume:21 Page:12806-12817
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Al-Ayoubi Samy R.¹²³⁴⁵,Schummel Paul Hendrik¹²³⁴⁵,Cisse Aline⁶⁷⁸⁹¹⁰^ORCID,Seydel Tilo⁶⁷⁸^ORCID,Peters Judith⁶⁷⁸⁹¹⁰^ORCID,Winter Roland¹²³⁴⁵^ORCID

Affiliation:

1. Physical Chemistry I – Biophysical Chemistry

2. Faculty of Chemistry and Chemical Biology

3. TU Dortmund University

4. 44227 Dortmund

5. Germany

6. Institut Laue Langevin

7. F-38042 Grenoble Cedex 9

8. France

9. University Grenoble Alpes

10. LiPhy

Abstract

We present a study of the combined effects of natural cosolvents (TMAO, glycine, urea) and pressure on the activity of the tetrameric enzyme lactate dehydrogenase (LDH).

Funder

Deutsche Forschungsgemeinschaft

Deutscher Akademischer Austauschdienst

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CP/C9CP02310K

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