1,5-Benzodiazepine derivatives as potential antimicrobial agents: design, synthesis, biological evaluation, and structure–activity relationships-Reference-Cited by-同舟云学术

1,5-Benzodiazepine derivatives as potential antimicrobial agents: design, synthesis, biological evaluation, and structure–activity relationships

Published:2015 Issue:19 Volume:13 Page:5497-5509
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wang Lan-Zhi¹²³⁴,Li Xiao-Qing¹²³⁴,An Ying-Shuang¹²³⁴

Affiliation:

1. College of Chemistry & Material Science

2. Hebei Normal University

3. Shijiazhuang 050024

4. People's Republic of China

Abstract

36 novel 1,5-benzodiazepine derivatives were synthesized and evaluated for their in vitro antimicrobial activity. The results revealed that most of the 1,5-benzodiazepine derivatives exhibited considerable potency against all of the tested strains.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00655D

Reference23 articles.

1. 1,5-Benzodiazepines VIII Novel 4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine derivatives with analgesic or anti-inflammatory activity

2. Tolerance to anticonvulsant effects of some benzodiazepines in genetically epilepsy prone rats

3. Synthesis of some new 4(3H)-quinazolinone-2-carboxaldehyde thiosemicarbazones and their metal complexes and a study on their anticonvulsant, analgesic, cytotoxic and antimicrobial activities – Part-1

4. 5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice

5. An efficient synthesis of 1,5-benzodiazepine derivatives catalyzed by boric acid

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