Metabolomics approach to identify therapeutically potential biomarkers of the Zhi-Zi-Da-Huang decoction effect on the hepatoprotective mechanism-Reference-Cited by-同舟云学术

Metabolomics approach to identify therapeutically potential biomarkers of the Zhi-Zi-Da-Huang decoction effect on the hepatoprotective mechanism

Published:2015 Issue:102 Volume:5 Page:84048-84055
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

An Li¹²³⁴,Shi Qingshui⁵⁶⁴,Feng Fang¹²³⁴⁷

Affiliation:

1. Department of Pharmaceutical Analysis

2. China Pharmaceutical University

3. Nanjing 210009

4. China

5. Jiangsu Institute for Food and Drug Control

6. Nanjing 210008

7. Key Laboratory of Drug Quality Control and Pharmacovigilance

Abstract

A NMR-based metabolomics approach was applied to find potential plasma and liver biomarkers responsible for the hepatoprotective effects of Zhi-Zi-Da-Huang decoction (ZZDHD).

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA16563F

Reference31 articles.

1. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

2. NMR spectroscopy of human post mortem cerebrospinal fluid: Distinction of Alzheimer's disease from control using pattern recognition and statistics

3. A1H NMR-based metabonomic investigation of time-dependent metabolic trajectories in a high salt-induced hypertension rat model

4. NMR-based metabolomic studies reveal changes in biochemical profile of urine and plasma from rats fed with sweet potato fiber or sweet potato residue

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