Solvent-mediated phase transformation between two tegafur polymorphs in several solvents-Reference-Cited by-同舟云学术

Solvent-mediated phase transformation between two tegafur polymorphs in several solvents

Published:2014 Issue:46 Volume:16 Page:10581-10591
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Bobrovs Raitis¹²³⁴⁵,Seton Linda⁵⁶⁷⁸,Actiņš Andris¹²³⁴

Affiliation:

1. Faculty of Chemistry

2. University of Latvia

3. Kr. Valdemara iela 48

4. Riga, Latvia

5. Formulation and Drug Delivery Research Group

6. School of Pharmacy and Biomolecular Sciences

7. Liverpool John Moores University

8. Liverpool, UK

Abstract

Here we show that the solvent-mediated polymorphic transformation rate depends linearly on the difference between equilibrium solubilities of tegafur polymorphs.

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/CE/C4CE01215A

Reference54 articles.

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2. Pharmaceutical Applications of Polymorphism

3. R. Hilfiker , Polymorphism in the Pharmaceutical Industry , ed. R. Hilfiker , Wiley-VCH , Weinheim , 2006 , p. 433

4. Crystalline solids

5. H. G. Brittain , Polymorphism in Pharmaceutical Solids , ed. H. G. Brittain , Informa Healthcare USA, Inc. , New York, NY , 2nd edn, 2009 , vol. 192 , p. 640

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