Multi-GBq production of the radiotracer [18F]fallypride in a droplet microreactor-Reference-Cited by-同舟云学术

Multi-GBq production of the radiotracer [18F]fallypride in a droplet microreactor

Published:2020 Issue:13 Volume:10 Page:7828-7838
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Jia¹²³⁴⁵^ORCID,Chao Philip H.¹²³⁴⁵^ORCID,Slavik Roger⁶⁷⁸⁴⁵,van Dam R. Michael¹²³⁴⁵^ORCID

Affiliation:

1. Department of Bioengineering

2. Henry Samueli School of Engineering

3. UCLA

4. Los Angeles

5. USA

6. Ahmanson Translational Imaging Division

7. David Geffen School of Medicine

8. University of California

Abstract

Using a micro-cartridge based radionuclide concentrator enables the production of multiple (10 s) of clinical doses of the PET tracer [¹⁸F]fallypride with a droplet micro-reactor platform (8 μL).

Funder

National Institute of Mental Health

National Cancer Institute

National Institute on Aging

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA01212B

Reference24 articles.

1. Microreactors for radiopharmaceutical synthesis

2. Radiolabelling diverse positron emission tomography (PET) tracers using a single digital microfluidic reactor chip

3. Microfluidic approach for fast labeling optimization and dose-on-demand implementation

4. Design and Optimization of Coin-Shaped Microreactor Chips for PET Radiopharmaceutical Synthesis

5. A simple microfluidic platform for rapid and efficient production of the radiotracer [18F]fallypride

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