Cytotoxicity evaluation and DNA interaction of RuII-bipy complexes containing coumarin-based ligands-Reference-Cited by-同舟云学术

Cytotoxicity evaluation and DNA interaction of RuII-bipy complexes containing coumarin-based ligands

Published:2021 Issue:41 Volume:50 Page:14908-14919
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

de Almeida Patrícia S. V. B.¹^ORCID,de Arruda Henrique Jefferson¹,Sousa Gleyton Leonel S.¹^ORCID,Ribeiro Felipe Vitório¹,de Azevedo-França José Aleixo²,Ferreira Larissa A.¹,Guedes Guilherme P.³,Silva Heveline⁴,Kummerle Arthur E.¹^ORCID,Neves Amanda P.¹^ORCID

Affiliation:

1. Instituto de Química, Universidade Federal Rural do Rio de Janeiro, BR 465 Km 7, 23890-000, Seropédica, RJ, Brazil

2. Instituto de Ciências Exatas, Departamento de Química, Universidade Federal de Juiz de Fora, MG, Brazil

3. Instituto de Química, Universidade Federal Fluminense, Niterói, RJ, Brazil

4. Instituto de Ciências Exatas, Departamento de Química, Universidade Federal de Minas Gerais, MG, Brazil

Abstract

Cationic RuII complexes derived from coumarin hybrids and bipyridine have shown greater cytotoxicity than the free ligands. Our findings have been associated to the strongest ability of the complexes to interact with DNA.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D1DT01567B

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