miR-122 plays an important role in ochratoxin A-induced hepatocyte apoptosis in vitro and in vivo-Reference-Cited by-同舟云学术

miR-122 plays an important role in ochratoxin A-induced hepatocyte apoptosis in vitro and in vivo

Published:2016 Issue:1 Volume:5 Page:160-167
ISSN:2045-452X
Container-title:Toxicology Research
language:en
Short-container-title:Toxicol. Res.

Author:

Zhu Liye¹²³⁴,Yu Tao¹²³⁴,Qi Xiaozhe¹²³⁴,Yang Bo¹²³⁴,Shi Lei¹²³⁴,Luo Haoshu⁵²³⁴,He Xiaoyun¹²³⁴⁶,Huang Kunlun¹²³⁴⁶,Xu Wentao¹²³⁴⁶

Affiliation:

1. College of Food Science and Nutritional Engineering

2. China Agricultural University

3. Beijing

4. China

5. College of Biological Sciences

6. The Supervision

Abstract

We compared OTA hepatotoxicity in vivo and in vitro. miR-122 regulated the CCNG1/p53 pathway in OTA-induced hepatocyte apoptosis. miR-122 also regulated the Bcl-w/caspase-3 pathway in OTA-induced hepatocyte apoptosis.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://pubs.rsc.org/en/content/articlepdf/2016/TX/C5TX00104H

Reference42 articles.

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