Investigation on chloro-bridged binuclear copper(<scp>ii</scp>) complexes as potent metallodrug candidates against colon cancer <i>via</i> chemical and biological assessments-Reference-Cited by-同舟云学术

Investigation on chloro-bridged binuclear copper(ii) complexes as potent metallodrug candidates against colon cancer via chemical and biological assessments

Published:2024 Issue:8 Volume:48 Page:3741-3757
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Sankar Neethu¹²^ORCID,Devarajan Badhmapriya²^ORCID,Manimuthu Akilesh²^ORCID,Nattamai S. P. Bhuvanesh³^ORCID,Nallasamy Dharmaraj²^ORCID,Velusamy Kaveri Machampalayam²^ORCID

Affiliation:

1. Bharathiar Cancer Theranostics Research Centre, RUSA 2.0, Bharathiar University, Coimbatore – 641 046, India

2. Department of Chemistry, Bharathiar University, Coimbatore – 641 046, India

3. Department of Chemistry, Texas A&M University, College Station, TX 77843, USA

Abstract

Synthesized binuclear copper(ii) complexes have been utilized for catechol oxidase mimicking activity, DNA/BSA interactions, molecular docking and pharmacological potential assessment against colon cancer and normal skin cells through in vitro method.

Funder

Rashtriya Uchchatar Shiksha Abhiyan

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D3NJ05335K

Reference61 articles.

1. Advances in Copper Complexes as Anticancer Agents

2. DNA/protein interaction and cytotoxic activity of imidazole terpyridine derived Cu(ii)/Zn(ii) metal complexes

3. Dinuclear doubly bridged phenoxido copper(II) complexes as efficient anticancer agents

4. Bi- and trinuclear copper(I) compounds of 2,2,5,5-tetramethyl-imidazolidine-4-thione and 1,2-bis(diphenylphosphano)ethane: Synthesis, crystal structures, in vitro and in silico study of antibacterial activity and interaction with DNA and albumins

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