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Non-invasive single cell aptasensing in live cells and animals

  • Published:2024 Issue:13 Volume:15 Page:4770-4778
  • ISSN:2041-6520
  • Container-title:Chemical Science
  • language:en
  • Short-container-title:Chem. Sci.

Author:

Osman Eiman A.1,Rynes Thomas P.2ORCID,Wang Y. Lucia3ORCID,Mruk Karen2ORCID,McKeague Maureen13ORCID

Affiliation:

1. Department of Chemistry, Faculty of Science, McGill University, Montreal, QC H3A 0B8, Canada

2. Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA

3. Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H3G 1Y6, Canada

Abstract

A genetically encoded aptasensor platform for non-invasive measurement of drug distribution in cells and zebrafish was developed.

Funder

Canada Foundation for Innovation

Natural Sciences and Engineering Research Council of Canada

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

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