Synthetic analogs of stryphnusin isolated from the marine sponge Stryphnus fortis inhibit acetylcholinesterase with no effect on muscle function or neuromuscular transmission

Author:

Moodie Lindon W. K.1234,Žužek Monika C.56789,Frangež Robert56789,Andersen Jeanette H.10234,Hansen Espen10234,Olsen Elisabeth K.10234,Cergolj Marija1112789,Sepčić Kristina1112789,Hansen Kine Ø.10234,Svenson Johan12341

Affiliation:

1. Department of Chemistry

2. UiT The Arctic University of Norway

3. Tromsø

4. Norway

5. Institute of Preclinical Sciences

6. Veterinary faculty

7. University of Ljubljana

8. Ljubljana

9. Slovenia

10. Marbio

11. Department of Biology

12. Biotechnical Faculty

Abstract

The current study describes the AChE inhibitory effect of natural marine neuroactive compounds.

Funder

Norges Forskningsråd

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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