Recent Developments in the Synthesis and Biological Applications of Thiazine-Reference-Cited by-同舟云学术

Recent Developments in the Synthesis and Biological Applications of Thiazine

Published:2024-07-24 Issue: Volume: Page:259-281
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Container-title:S-Heterocycles
language:en
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Author:

Thube D. R.¹,Akolkar H. N.²,Darekar N. R.³,Khedkar V. M.⁴,Kundlikar S. G.⁵

Affiliation:

1. P.G. and Research Centre, Department of Chemistry, New Arts Commerce and Science College a , Parner, District Ahmednagar, Maharashtra, 414302 , India

2. Department of Chemistry, Abasaheb Marathe Arts and New Commerce, Science College b , Rajapur, Ratnagiri, Maharashtra, 416702 , India

3. P.G. and Research, Department of Chemistry, Radhabai Kale Mahila Mahavidyalaya c , Ahmednagar, Maharashtra, 414001 , India

4. School of Pharmacy, Vishwakarma University d , Pune, Maharashtra, 411048 , India

5. P.G. and Research Centre, Department of Chemistry, New Arts Commerce and Science College a , Parner, District Ahmednagar, Maharashtra, 414302 , India saritakundlikar1@gmail.com

Abstract

Thiazines played a significant role in medicinal chemistry. Their derivatives have a wide spectrum of biological activities. In this chapter, we described the most recent information on various synthesis techniques and the biological importance of thiazine derivatives from the published research papers.

Publisher

Royal Society of Chemistry

Link

https://books.rsc.org/books/edited-volume/chapter-pdf/1830397/bk9781837674015-00259.pdf

Reference48 articles.

1. One-Pot Synthesis of Benzo[1,4]thiazin-3(4H)-ones and a Theoretical Study of the S-N Type Smiles Rearrangement Mechanism;Zhao;J. Org. Chem.,2012

2. Ph3P-mediated one-pot synthesis of functionalized 3,4-dihydro-2H-1,3-thiazines from N,N′-dialkylthioureas and activated acetylenes in water;Hossaini;Monatsh. Chem.,2010

3. Bioactive Thiazine and Benzothiazine Derivatives: Green Synthesis Methods and Their Medicinal Importance;Badshah;Molecules,2016

4. Synthesis, spectroscopic studies, DFT calculations, antimicrobial and antitumor activity of tridentate NNO Schiff base metal complexes based on 5-acetyl-4-hydroxy-2H-1,3-thiazine-2,6(3H)-dione;Adly;J. Mol. Struct.,2019

5. Discovery of an Extremely Potent Thiazine-Based β-Secretase Inhibitor with Reduced Cardiovascular and Liver Toxicity at a Low Projected Human Dose;Tadano;J. Med. Chem.,2019