Genotoxic, Biochemical and Physiological Biomarkers Triggered by Agrochemicals in Neotropical Anuran Species

Author:

Pérez-Iglesias Juan Manuel12,Bach Nadia C.3,Cid Fabricio D.3,Franco-Belussi Lilian45,de Arcaute Celeste Ruiz6,Salla Raquel7

Affiliation:

1. Laboratorio de Química Analítica Ambiental, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Facultad de Ciencias de la Salud, Universidad Nacional de San Luis (UNSL) a Ejército de los Andes 950 (D5700BWS), San Luis Argentina jpereziglesias@unlc.edu.ar

2. Departamento de Ciencias Ambientales y Producción, Universidad Nacional de Los Comechingones (UNLC), Héroes de Malvinas 1587 (CP5881) b Villa de Merlo, San Luis Argentina

3. Área de Biología, Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis (UNSL) c Ejército de los Andes 950 (D5700BWS), San Luis Argentina

4. Department of Biological Sciences, São Paulo State University (UNESP) d Cristóvão Colombo 2265, 15054-000, São José do Rio Prêto Brazil

5. Laboratório de Patologia Experimental, Universidade Federal de Mato Grosso do Sul (UFMS) e Avenida Costa e Silva s/n, 79070-900, Campo Grande Brazil

6. Cátedra de Citología, Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata (UNLP) f Calle 64 N° 3, B1904AMA La Plata, Buenos Aires Argentina

7. Federal University of São Carlos (Campus Sorocaba) g João Leme dos Santos Highway, km 110 -SP-264, Itinga, Sorocaba, São Paulo Brazil

Abstract

At present, there are two key features of Neotropical amphibians’ biodiversity: one is that it is amazing and the other is that it is disappearing. This region has the highest diversity of species containing more species of amphibians than tropical Africa and Southeast Asia combined. Examination of assessment data for all Neotropical anuran species shows that modern agricultural practises top the list of threats, posing risks to up to 30% of all the assessed species. This type of agriculture makes use of a wide range of agrochemicals for genetically modified tolerant seeds. In this context, biomarkers, understood as the cellular, biochemical, physiological or histological quality in living organisms to assess the exposure or effect of xenobiotics, including agrochemicals, can provide connection clues on the exposure and biological responses in amphibians such as anurans. The information obtained from these sources can be later valid in the field for implementing environmental risk assessment strategies. The chapter aims to describe the use of biomarkers at the genetic, biochemical and physiological levels to validate their usefulness as endpoints in Neotropical anuran species to be used as validating tools indicating genotoxicology and ecotoxicology due to exposure to xenobiotics.

Publisher

Royal Society of Chemistry

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