Abstract
Diazomethane is a chemical compound with molecular formula CH2N2. Because of the partial negative charge on the carbon it acts as a nucleophile as well as a base. It is also a powerful 1,3-dipole, meaning that it is a dipole with delocalisation over three atoms. This chapter discusses the current production and use of diazomethane, before looking at the ways of working in flow instead of in batch reactions, which can make the production processes safer.
Publisher
The Royal Society of Chemistry