Direct radiofluorination of a heat-sensitive antibody by Al–18F complexation

Author:

Huynh Phuong Tu12345ORCID,Soni Nisarg12345,Pal Rammyani12345,Sarkar Swarbhanu12345,Jung Jung-Min12345,Lee Woonghee12345,Yoo Jeongsoo12345

Affiliation:

1. Department of Molecular Medicine

2. BK21 Plus KNU Biomedical Convergence Program

3. School of Medicine

4. Kyungpook National University

5. Daegu

Abstract

A heat-sensitive antibody conjugated with the NODA chelator was successfully radiolabeled at 30 °C using Al–18F complexation without immunoreactivity loss.

Funder

Ministry of Science, ICT and Future Planning

Ministry of Health and Welfare

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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