A food web bioaccumulation model for the accumulation of per- and polyfluoroalkyl substances (PFAS) in fish: how important is renal elimination?-Reference-Cited by-同舟云学术

A food web bioaccumulation model for the accumulation of per- and polyfluoroalkyl substances (PFAS) in fish: how important is renal elimination?

Published:2022 Issue:8 Volume:24 Page:1152-1164
ISSN:2050-7887
Container-title:Environmental Science: Processes & Impacts
language:en
Short-container-title:Environ. Sci.: Processes Impacts

Author:

Sun Jennifer M.¹^ORCID,Kelly Barry C.²³^ORCID,Gobas Frank A. P. C.³,Sunderland Elsie M.¹^ORCID

Affiliation:

1. Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA, 02138

2. Meta Analytical Inc., Calgary, AB, T3H 2Z5, Canada

3. School of Resource and Environmental Management, Faculty of the Environment, Simon Fraser University, Burnaby, British Columbia, V5A 1S6, Canada

Abstract

We present a whole-body aquatic food web bioaccumulation model for perfluoroalkyl acids and two alternatives. Results highlight structure-dependent mechanisms, including phospholipid partitioning, blood plasma protein binding, and renal elimination.

Funder

National Institute of Environmental Health Sciences

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Management, Monitoring, Policy and Law,Public Health, Environmental and Occupational Health,Environmental Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/EM/D2EM00047D

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