A new route to dithia- and thiaoxacyclooctynes via Nicholas reaction-Reference-Cited by-同舟云学术

A new route to dithia- and thiaoxacyclooctynes via Nicholas reaction

Published:2014 Issue:30 Volume:4 Page:15493-15495
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Hagendorn Tobias¹²³,Bräse Stefan¹²³⁴⁵

Affiliation:

1. Institute of Organic Chemistry

2. Karlsruhe Institute of Technology

3. 76131 Karlsruhe, Germany

4. Institute of Toxicology and Genetics

5. KIT

Abstract

By using the Nicholas reaction we managed to design a concise synthesis that only uses three steps to build the eight-membered ring. It was also possible to functionalize said alkyne with a fluorophore.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA01345J

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