Synthesis of 5-trifluoromethyl-1,2,3-triazoles via base-mediated cascade annulation of diazo compounds with trifluoroacetimidoyl chlorides-Reference-Cited by-同舟云学术

Synthesis of 5-trifluoromethyl-1,2,3-triazoles via base-mediated cascade annulation of diazo compounds with trifluoroacetimidoyl chlorides

Published:2021 Issue:13 Volume:8 Page:3440-3445
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Yang Hefei¹²³⁴,Xu Tian-Hui¹²³⁴,Lu Shu-Ning¹²³⁴,Chen Zhengkai¹²³⁴^ORCID,Wu Xiao-Feng⁵⁶⁷⁸⁹^ORCID

Affiliation:

1. Department of Chemistry

2. Zhejiang Sci-Tech University

3. Hangzhou 310018

4. People's Republic of China

5. Dalian National Laboratory for Clean Energy

6. Dalian Institute of Chemical Physics

7. Chinese Academy of Sciences

8. Dalian 116023

9. China

Abstract

A metal-, azide- and CF₃-reagent free approach for the synthesis of 5-trifluoromethyl-1,2,3-triazoles via base-mediated cascade annulation of diazo compounds with trifluoroacetimidoyl chlorides has been developed.

Funder

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00445J

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