Novel benzothiazole based sulfonylureas/sulfonylthioureas: design, synthesis and evaluation of their antidiabetic potential-Reference-Cited by-同舟云学术

Novel benzothiazole based sulfonylureas/sulfonylthioureas: design, synthesis and evaluation of their antidiabetic potential

Published:2016 Issue:8 Volume:40 Page:6777-6786
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Kharbanda Chetna¹²³⁴⁵,Alam Mohammad Sarwar¹²³⁴⁵,Hamid Hinna¹²³⁴⁵,Javed Kalim¹²³⁴⁵,Bano Sameena¹²³⁴⁵,Ali Yakub¹²³⁴⁵,Dhulap Abhijeet⁶⁷⁵,Alam Parwez⁸⁹¹⁰⁵,Pasha M. A. Q.⁸⁹¹⁰⁵

Affiliation:

1. Department of Chemistry

2. Faculty of Science

3. Hamdard University

4. New Delhi-110 062

5. India

6. CSIR Unit for Research and Development of Information Products

7. Pune-411038

8. Functional Genomics Unit

9. CSIR-Institute of Genomics & Integrative Biology

10. Delhi

Abstract

Twenty-eight benzothiazole based sulfonylureas/sulfonylthioureas were synthesized and were found to be effective against diabetes as PPAR-γ agonists.

Funder

University Grants Committee

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/NJ/C5NJ03589A

Reference21 articles.

1. Peroxisome Proliferator–Activated Receptor γ and Metabolic Disease

2. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

3. Sulfonylurea Agents Exhibit Peroxisome Proliferator-activated Receptor γ Agonistic Activity

4. Sulfonylureas and Glinides Exhibit Peroxisome Proliferator-Activated Receptor γ Activity: A Combined Virtual Screening and Biological Assay Approach

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