A novel method for simultaneously screening superoxide anion scavengers and xanthine oxidase inhibitors using hydroethidine as a fluorescent probe coupled with high-performance liquid chromatography-mass spectrometry
Author:
Affiliation:
1. Department of Pharmacognosy
2. State Key Laboratory of Natural Medicines
3. China Pharmaceutical University
4. Nanjing 210009
5. P. R. China
6. School of Life Sciences
7. Zhaoqing University
8. Zhaoqing 526061
Abstract
Excess reactive oxygen species can cause cellular damage, and are involved in many pathological processes such as inflammation, atherosclerosis and cancer.
Funder
National Basic Research Program of China
Department of Education of Guangdong Province
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/AY/C9AY02059D
Reference30 articles.
1. Superoxide generated by pyrogallol reduces highly water-soluble tetrazolium salt to produce a soluble formazan: A simple assay for measuring superoxide anion radical scavenging activities of biological and abiological samples
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4. Modulating cancer multidrug resistance by sertraline in combination with a nanomedicine
5. An ultrasensitive fluorescent assay for the in vivo quantification of superoxide radical in organisms
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