Portable sample processing for molecular assays: application to Zika virus diagnostics-Reference-Cited by-同舟云学术

Portable sample processing for molecular assays: application to Zika virus diagnostics

Published:2022 Issue:9 Volume:22 Page:1748-1763
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Narahari Tanya¹²,Dahmer Joshua¹,Sklavounos Alexandros¹²^ORCID,Kim Taehyeong¹²^ORCID,Satkauskas Monika¹,Clotea Ioana¹,Ho Man¹²,Lamanna Julian¹²,Dixon Christopher¹^ORCID,Rackus Darius G.¹³^ORCID,Silva Severino Jefferson Ribeiro da⁴^ORCID,Pena Lindomar⁴,Pardee Keith³⁵,Wheeler Aaron R.¹²⁶^ORCID

Affiliation:

1. Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, M5S 3H6, Canada

2. Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario, M5S 3E1, Canada

3. Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, M5S 3M2, Canada

4. Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Institute (FIOCRUZ Pernambuco), Av. Professor Moraes Rego, s/n – Cidade Universitária, Recife, PE, CEP 50.740-465, Brazil

5. Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, M5S 3G8 Canada

6. Institute for Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario, M5S 3G9, Canada

Abstract

A digital microfluidic system was developed for portable Zika virus diagnosis, featuring integrated, automated sample extraction and amplification.

Funder

Canadian Institutes of Health Research

International Development Research Centre

University of Toronto

Natural Sciences and Engineering Research Council of Canada

Canada Research Chairs

Publisher

Royal Society of Chemistry (RSC)