Determination of nine prohibited N-nitrosamines in cosmetic products by vortex-assisted dispersive liquid–liquid microextraction prior to gas chromatography-mass spectrometry

Author:

Schettino Lorenza1,Benedé Juan L.1,Chisvert Alberto1ORCID

Affiliation:

1. GICAPC Research Group, Department of Analytical Chemistry, University of Valencia, 46100 Burjassot, Valencia, Spain

Abstract

A sensitive analytical method for determining trace levels of nine banned N-nitrosamines in cosmetics is developed. Significant amounts of some of them, even exceeding the limits established by European legislation, were found in some samples.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference30 articles.

1. R.Fernández-Alba and A.Agüera , in Encyclopedia of Analytical Science , ed. P. Worsfold , A. Townshend and C. Poole , Elsevier , Amsterdam , 2nd edn, 2005 , vol. 6 , pp. 197–202

2. Scientific Committee on Consumer Safety , Opinion on Nitrosamines and Secondary Amines in Cosmetic Products , 2012

3. Fifteenth Commission Directive 92/86/EEC of 21 October 1992, Adapting to Technical Progress Annexes II, III, IV, V, VI and VII of Council Directive 76/768/EEC on the Approximation of the Laws of the Member States Relating to Cosmetic Products , 1992

4. Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on Cosmetic Products, and its Successive Amendments , 2009

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