Isolation of lingzhifuran A and lingzhilactones D–F from Ganoderma lucidum as specific Smad3 phosphorylation inhibitors and total synthesis of lingzhifuran A-Reference-Cited by-同舟云学术

Isolation of lingzhifuran A and lingzhilactones D–F from Ganoderma lucidum as specific Smad3 phosphorylation inhibitors and total synthesis of lingzhifuran A

Published:2016 Issue:81 Volume:6 Page:77887-77897
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ding Wei-Yi¹²³⁴⁵,Ai Jun⁶⁷⁸⁹¹⁰,Wang Xin-Long¹²³⁴⁵,Qiu Fayang G.¹¹¹²³¹³⁵,Lv Qing¹²³⁴⁵,Fang Ping¹²³⁴⁵,Hou Fan-Fan⁶⁷⁸⁹¹⁰,Yan Yong-Ming¹²³⁴⁵,Cheng Yong-Xian¹²³⁴⁵

Affiliation:

1. State Key Laboratory of Phytochemistry and Plant Resources in West China

2. Kunming Institute of Botany

3. Chinese Academy of Sciences

4. Kunming 650204

5. People's Republic of China

6. State Key Laboratory of Organ Failure Research

7. National Clinical Research Center for Kidney Disease

8. Division of Nephrology

9. Nanfang Hospital

10. Southern Medical University

11. Laboratory of Molecular Engineering and Laboratory of Natural Product Synthesis

12. Guangzhou Institutes of Biomedicine and Health

13. Guangzhou

Abstract

Lingzhifuran A (1) and lingzhilactones D–F (2–4), four new phenolic meroterpenoids were isolated from the fruiting bodies of Ganoderma lucidum. Total synthesis and biological evaluation of lingzhifuran A were carried out herein.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA17900B

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