Synthesis of benzofused cyclobutaoxepanones via intramolecular annulation of o-cinnamyl chalcones
Author:
Affiliation:
1. Department of Medicinal and Applied Chemistry
2. Kaohsiung Medical University
3. Kaohsiung 807
4. Taiwan
5. Department of Medical Research
Abstract
Baylis–Hillman type intramolecular stereoselective annulation of o-cinnamyloxy chalcones provides tricyclic benzofused cyclobutaoxepanones via two kinds of [2 + 2] cyclizations. Diversified reaction conditions have been investigated for one-pot facile, high-yield transformation.
Funder
Ministry of Science and Technology
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00058F
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