Two-photon fluorescent polydopamine nanodots for CAR-T cell function verification and tumor cell/tissue detection-Reference-Cited by-同舟云学术

Two-photon fluorescent polydopamine nanodots for CAR-T cell function verification and tumor cell/tissue detection

Published:2018 Issue:40 Volume:6 Page:6459-6467
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Ma Baojin¹²³⁴,Liu Feng¹²³⁴,Zhang Shan¹²³⁴^ORCID,Duan Jiazhi¹²³⁴,Kong Ying¹²³⁴,Li Zhao¹²³⁴,Tang Dongqi⁵⁶³⁴,Wang Wenjuan⁵⁶³⁴,Ge Shaohua⁷⁸²³⁴,Tang Wei⁹²³⁴,Liu Hong¹²³⁴¹⁰^ORCID

Affiliation:

1. State Key Laboratory of Crystal Materials

2. Shandong University

3. Jinan

4. China

5. Center for Stem Cell & Regenerative Medicine

6. The Second Hospital of Shandong University

7. Shandong Provincial Key Laboratory of Oral Tissue Regeneration

8. School of Stomatology

9. School of Basic Medical Science

10. Institute for Advanced Interdisciplinary Research

Abstract

OPDA nanodots were used to verify CAR-T cells function and efficiency through visible fluorescence. PDA nanodots can in situ convert to OPDA by the oxidation of ROS in cells to identify the tumor and normal cells/tissues.

Funder

National Natural Science Foundation of China

Shandong University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2018/TB/C8TB01930D

Reference37 articles.

1. Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits

2. Driving CAR T-cells forward