Construction of fully substituted carbon centers containing a heteroatom and a CF3 group via in situ generated p-quinone methides-Reference-Cited by-同舟云学术

Construction of fully substituted carbon centers containing a heteroatom and a CF3 group via in situ generated p-quinone methides

Published:2021 Issue:6 Volume:19 Page:1305-1314
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Terashima Kyu¹²³⁴⁵,Kawasaki-Takasuka Tomoko¹²³⁴⁵,Yamazaki Takashi¹²³⁴⁵^ORCID

Affiliation:

1. Division of Applied Chemistry

2. Institute of Engineering

3. Tokyo University of Agriculture and Technology

4. Koganei 184-8588

5. Japan

Abstract

Facile and practical construction of heteroatom as well as CF₃-containing fully substituted carbon centers was realized by 1,6-conjugate additions of a variety of heteronucleophiles to in situ generated δ-CF₃-δ-substituted p-quinone methides.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB02469D

Reference64 articles.

1. Recent Advances in the Catalytic Enantioselective Reactions of para -Quinone Methides

2. para -Quinone Methides as Acceptors in 1,6-Nucleophilic Conjugate Addition Reactions for the Synthesis of Structurally Diverse Molecules

3. Gold-catalyzed tandem reaction of 2-alkynylanilines followed by 1,6-conjugate addition to p-quinone methides: efficient access to unsymmetrical diarylindolylmethanes

4. Base-Mediated 1,6-Aza-Michael Addition of Heterocyclic Amines and Amides to para-Quinone Methides Leading to Meclizine-, Hydroxyzine- and Cetirizine-like Architectures

5. Synthesis of 2,4‐Diaryl‐1,3‐benzoxazines via FeCl 3 ‐Catalyzed Annulation of ortho ‐Hydroxyphenyl‐Substituted para ‐Quinone Methides with Imidates

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Construction of CF<sub>3</sub>-containing Tetrasubstituted Carbon Frameworks by Way of <i>p</i>-Quinone Methides;Journal of Synthetic Organic Chemistry, Japan;2023-03-01

2. Synthesis and synthetic applications of (4-hydroxyphenyl)perfluoroalkylmethanols;Tetrahedron;2022-01