Design and synthesis of an environment-sensitive 3-methyleneisoindolin-1-one fluorophore for labeling DNA-interacting proteins-Reference-Cited by-同舟云学术

Design and synthesis of an environment-sensitive 3-methyleneisoindolin-1-one fluorophore for labeling DNA-interacting proteins

Published:2024 Issue:35 Volume:22 Page:7231-7239
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Aso Mariko¹^ORCID,Ohta Chiyoe²,Liu Yixuan¹,Sasaki-Tabata Kaori¹,Abe-Sadamatsu Yukiko¹,Gatanaga Chiemi¹,Wang Yichun¹,Pei Yang¹,Gao Guosheng¹,Katayama Tsutomu¹,Taniguchi Yosuke¹^ORCID,Sasaki Shigeki³^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan

2. Faculty of Pharmaceutical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan

3. Faculty of Pharmaceutical Sciences, Nagasaki International University, 2825-7, Huis Ten Bosche Machi, Sasebo 859-3298, Japan

Abstract

A new environment-sensitive fluorophore, 6-dimethylamino 3-methyleneisoindolinone, and reactive oligodeoxynucleotides for turn-on fluorescent lysine modification of target protein were developed.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB01036A

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