Diversity-oriented routes to thiopeptide antibiotics: total synthesis and biological evaluation of micrococcin P2-Reference-Cited by-同舟云学术

Diversity-oriented routes to thiopeptide antibiotics: total synthesis and biological evaluation of micrococcin P2

Author:

Hwang Hee-Jong¹²^ORCID,Son Young-Jin¹³^ORCID,Kim Dahyun¹,Lee Jusuk¹,Shin Yun-Jeong³,Kwon Yonghoon³,Ciufolini Marco A.²^ORCID

Affiliation:

1. A&J Science Co., Ltd, 80 Chumbok Ro, Dong Gu, Daegu, 41061, Republic of Korea

2. Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6 K 1Z1, Canada

3. Department of Agricultural Biotechnology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea

Abstract

The first synthesis of micrococcin P2 has been achieved by late-stage Suzuki coupling of a macrocyclic boronic acid with a 2-bromothiazole.

Funder

National Research Foundation of Korea

Ministry of Health and Welfare

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

Reference49 articles.

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