Stereoselective separation, configuration determination, and quantification of flavanone glycosides in Citrus using chiral HPLC-UV in combination with CD spectra

Author:

Jiang Bingtong12,Wang Zhaokun2ORCID,Shi Xuejiao2,Gao Ying2,Zhang Jiayu2ORCID,Che Yanyun1

Affiliation:

1. Engineering Research Center for Homology of Medicine and Food Beverage of Yunnan Province, College of Pharmaceutical Science, Yunnan University of Chinese Medicine, No. 1076 Yuhua Road, Chenggong District, Kunming 650500, Yunnan, China

2. School of Pharmacy, Binzhou Medical University, 346 Guanhai Road Laishan District, Yantai 264003, China

Abstract

A efficient method for simultaneous separation of the C-2 diastereomers of naringin, neohesperidin, hesperidin and narirutin was developed, and used for determination of each epimer of them in traditional Chinese medicine of Zhiqiao and Zhishi.

Funder

Yantai Science and Technology Bureau

Department of Science and Technology of Shandong Province

Health Commission of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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