First access to a mycolic acid-based bioorthogonal reporter for the study of the mycomembrane and mycoloyltransferases in Corynebacteria-Reference-Cited by-同舟云学术

First access to a mycolic acid-based bioorthogonal reporter for the study of the mycomembrane and mycoloyltransferases in Corynebacteria

Published:2019 Issue:87 Volume:55 Page:13074-13077
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Lesur Emilie¹²³⁴⁵,Baron Aurélie⁶⁷³⁴⁸,Dietrich Christiane⁹³⁴¹⁰⁵,Buchotte Marie¹²³⁴⁵^ORCID,Doisneau Gilles¹²³⁴⁵^ORCID,Urban Dominique¹²³⁴⁵^ORCID,Beau Jean-Marie¹²³⁴⁵^ORCID,Bayan Nicolas⁹³⁴¹⁰⁵^ORCID,Vauzeilles Boris¹²³⁴⁵^ORCID,Guianvarc’h Dominique¹²³⁴⁵^ORCID,Bourdreux Yann¹²³⁴⁵^ORCID

Affiliation:

1. Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO)

2. UMR 8182

3. Université Paris-Sud

4. Université Paris-Saclay

5. CNRS

6. Institut de Chimie des Substances Naturelles

7. CNRS UPR2301

8. F-91198 Gif-sur-Yvette

9. Institute for Integrative Biology of the Cell (I2BC)

10. CEA

Abstract

In this study we describe the first synthesis of an alkyne-based trehalose monomycolate probe closely mimicking the complex pattern of mycolic acids and its utility for the study of mycomembrane and mycoloyltransferases in Corynebacteria.

Funder

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC05754D

Reference49 articles.

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4. Mycolic Acids: Structures, Biosynthesis, and Beyond

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