An improved HPLC-MS/MS method for simultaneous quantification of propranolol and its two phase I metabolites in plasma of infants with hemangioma and its application to a comparative study of plasma concentrations-Reference-Cited by-同舟云学术

An improved HPLC-MS/MS method for simultaneous quantification of propranolol and its two phase I metabolites in plasma of infants with hemangioma and its application to a comparative study of plasma concentrations

Published:2018 Issue:65 Volume:8 Page:37286-37294
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

He Huan¹²³⁴⁵,Li Li⁶²³⁴⁵,Zhao Libo¹²³⁴⁵,Sun Ning¹²³⁴⁵,Zhang Meng¹²³⁴⁵,Cheng Ying⁶²³⁴⁵,Yu Lu⁶²³⁴⁵,Ma Lin⁶²³⁴⁵,Wang Xiaoling¹²³⁴⁵^ORCID

Affiliation:

1. Clinical Research Center

2. Beijing Children's Hospital

3. Capital Medical University

4. National Center for Children's Health

5. Beijing 100045

6. Department of Dermatology

Abstract

Comparative study of propranolol, 4-hydroxypropranolol and N-desisopropylpropranolol in the plasma of infants with hemangioma after oral administration of different doses of propranolol.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA06252H

Reference18 articles.

1. Infantile haemangioma

2. Safety of Oral Propranolol for the Treatment of Infantile Hemangioma: A Systematic Review

3. Initiation and Use of Propranolol for Infantile Hemangioma: Report of a Consensus Conference

4. Propranolol for Severe Hemangiomas of Infancy

5. Diagnosis and Management of Infantile Hemangiomas

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