Affiliation:
1. Institute of Pharmaceutical Science, King's College London, London, UK
Abstract
We demonstrate the VITAS (Viral polymerase-Inhibition Toxin-Associated Selection) assay for thein vivoselection and discovery of enzymes producing one of the largest groups of antivirals, namely antiviral nucleotide analogues (ANAs).
Funder
European Cooperation in Science and Technology
Royal Society
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis